{"id":1328,"date":"2013-11-02T10:43:19","date_gmt":"2013-11-02T01:43:19","guid":{"rendered":"https:\/\/seeds.web.nitech.ac.jp\/?p=1328"},"modified":"2020-02-05T16:15:13","modified_gmt":"2020-02-05T07:15:13","slug":"%e5%89%af%e4%bd%9c%e7%94%a8%e3%81%ae%e5%b0%91%e3%81%aa%e3%81%84%e8%96%ac%e7%89%a9%e5%be%90%e6%94%be%e6%8b%85%e4%bd%93%e3%81%ae%e6%a7%8b%e7%af%89","status":"publish","type":"post","link":"https:\/\/seeds.web.nitech.ac.jp\/?p=1328","title":{"rendered":"\u526f\u4f5c\u7528\u306e\u5c11\u306a\u3044\u85ac\u7269\u5f90\u653e\u62c5\u4f53\u306e\u69cb\u7bc9"},"content":{"rendered":"<h4><strong>\uff5e\u50c5\u304b\u306a\u74b0\u5883\u5909\u5316\u3067\u958b\u9589\u3059\u308b\u5206\u5b50\u30b2\u30fc\u30c8\uff5e<\/strong><\/h4>\n<h2>\u526f\u4f5c\u7528\u306e\u5c11\u306a\u3044\u85ac\u7269\u5f90\u653e\u62c5\u4f53\u306e\u69cb\u7bc9<\/h2>\n<table class=\"seeds-head\">\n<tbody>\n<tr>\n<td><strong>\u7814\u7a76\u5206\u91ce\u5206\u985e\uff1a<\/strong>5303 \u9ad8\u5206\u5b50\u5316\u5b66<br 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\/>\n<\/strong>\u3000\u5f53\u7814\u7a76\u5ba4\u3067\u306f\u3001\u526f\u4f5c\u7528\u306e\u5c11\u306a\u3044\u85ac\u7269\u9664\u653e\u62c5\u4f53\u306e\u69cb\u7bc9\u306b\u53d6\u308a\u7d44\u3093\u3067\u3044\u307e\u3059\u3002\u672c\u7814\u7a76\u306f\u3001\u304c\u3093\u7d30\u80de\u304c\u4ed6\u306e\u6b63\u5e38\u7d30\u80de\u3068\u6bd4\u8f03\u3057\u3066\u3001\u305d\u306e\u5468\u8fba\u306e\uff50H\u304c\u9178\u6027\u306b\u50be\u3044\u3066\u3044\u308b\u3053\u3068\u3092\u5229\u7528\u3057\u3066\u3001\u304c\u3093\u7d30\u80de\u306e\u8fd1\u508d\u3067\u306e\u307f\u85ac\u7269\u3092\u9664\u653e\u51fa\u3059\u308b\u5206\u5b50\u30b2\u30fc\u30c8\u3092\u6301\u3064\u85ac\u7269\u9664\u653e\u51fa\u62c5\u4f53\u306e\u69cb\u7bc9\u3092\u76ee\u7684\u3068\u3057\u305f\u3082\u306e\u3067\u3059\u3002<\/td>\n<td><\/td>\n<td><strong>\u7279\u5fb4<br \/>\n<\/strong>\u3000\u79c1\u305f\u3061\u306e\u65b0\u3057\u3044\u85ac\u7269\u62c5\u4f53\u306f\u3001\u30ca\u30ce\u30b5\u30a4\u30ba\u306e\u201d\u5b54\u201d\u3092\u591a\u6570\u3082\u3064\u30b7\u30ea\u30ab\u7c92\u5b50\u306e\u8868\u9762\u3092\u8986\u3046\u3088\u3046\u306b\u898f\u5247\u6b63\u3057\u304f\u4e26\u3093\u3060\u5206\u5b50\u3067\u201d\u84cb\u201d\u3092\u3057\u307e\u3059\u3002\u3053\u306e\u5206\u5b50\u306f\u3001\u50c5\u304b\u306a\uff50H\u306e\u5909\u5316\u3092\u898b\u6975\u3081\u3001\u305d\u306e\u5f62\u304c\u5909\u5316\u3057\u3066\u3001\u8986\u3063\u3066\u3044\u305f\u201d\u5b54\u201d\u3092\u958b\u653e\u3057\u3001\u201d\u5b54\u201d\u306b\u9589\u3058\u8fbc\u3081\u3089\u308c\u3066\u3044\u305f\u85ac\u7269\u304c\u653e\u51fa\u3057\u307e\u3059\u3002\u3064\u307e\u308a\u3001\u201d\u5b54\u201d\u3092\u8986\u3063\u3066\u3044\u308b\u5206\u5b50\u306f\u50c5\u304b\u306a\uff50H\u5909\u5316\u306b\u5fdc\u7b54\u3059\u308b\u5206\u5b50\u30b2\u30fc\u30c8\u3068\u3057\u3066\u50cd\u304d\u307e\u3059\u3002<\/td>\n<\/tr>\n<tr>\n<td><strong>\u80cc\u666f\u30fb\u5f93\u6765\u6280\u8853<br \/>\n<\/strong>\u3000\u3053\u308c\u307e\u3067\u306e\u6297\u304c\u3093\u5264\u3092\u7528\u3044\u305f\u6cbb\u7642\u3067\u306f\u3001\u5f37\u3044\u526f\u4f5c\u7528\u304c\u3042\u308a\u3001\u4f7f\u7528\u3059\u308b\u85ac\u7269\u304c\u9650\u3089\u308c\u3066\u3044\u307e\u3057\u305f\u3002\u60a3\u90e8\u306e\u307f\u3067\u85ac\u7269\u3092\u653e\u51fa\u3059\u308b\u3053\u3068\u304c\u53ef\u80fd\u306a\u3001\u3064\u307e\u308a\u3001\u50c5\u304b\u306a\u74b0\u5883\u5909\u5316\u3092\u8a8d\u8b58\u3057\u3066\u3001\u85ac\u7269\u306e\u653e\u51fa\u91cf\u304c\u5236\u5fa1\u3067\u304d\u308c\u3070\u3001\u3053\u308c\u307e\u3067\u4f7f\u7528\u3067\u304d\u306a\u304b\u3063\u305f\u85ac\u7269\u306e\u4f7f\u7528\u3082\u53ef\u80fd\u3068\u306a\u308a\u307e\u3059\u3002<\/td>\n<td><\/td>\n<td><strong>\u5b9f\u7528\u5316\u30a4\u30e1\u30fc\u30b8<\/strong><br \/>\n\u3000\u3053\u306e\u85ac\u7269\u9664\u653e\u5358\u4f53\u3092\u7528\u3044\u308b\u3068\u3001\u304c\u3093\u7d30\u80de\u306e\u5468\u308a\u3060\u3051\u3067\u6297\u304c\u3093\u5264\u3092\u653e\u51fa\u3057\u3066\u3001\u6b63\u5e38\u306a\u7d30\u80de\u306f\u50b7\u3064\u3051\u306a\u3044\u3001\u5fae\u5c0f\u74b0\u5883\u5909\u5316\u306b\u5fdc\u7b54\u3057\u305f\u85ac\u7269\u9664\u653e\u51fa\u304c\u53ef\u80fd\u3068\u306a\u308a\u307e\u3059\u3002<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p><a href=\"https:\/\/seeds.web.nitech.ac.jp\/wp-content\/uploads\/2013\/11\/image5.png\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" src=\"https:\/\/seeds.web.nitech.ac.jp\/wp-content\/uploads\/2013\/11\/image_thumb5.png\" width=\"387\" height=\"240\" border=\"0\" \/><\/a><br \/>\n\u50c5\u304b\u306a\uff50H\u5909\u5316\u306b\u5fdc\u7b54\u3057\u3066\u85ac\u7269\u3092\u653e\u51fa\u3059\u308b\u5f90\u653e\u62c5\u4f53\u69cb\u7bc9\u306e\u6a21\u5f0f\u56f3\u3068\u305d\u306e\u85ac\u7269\u5f90\u653e\u306e\u6a5f\u69cb\u3002\u5869\u57fa\u6027\u6761\u4ef6\u4e0b\uff08\uff50H\uff18\uff09\u3067\u306f\u3001\u8868\u9762\u306e\u30da\u30d7\u30c1\u30c9\u5206\u5b50\u304c\u5206\u5b50\u9593\u6c34\u7d20\u7d50\u5408\u306b\u3088\u308a\u3001\u30b7\u30fc\u30c8\u72b6\u306e\u69cb\u9020\u3092\u5f62\u6210\u3057\u5b54\u3092\u585e\u3050\u3002\u9006\u306b\u3001\u9178\u6027\uff08\uff50H6)\u3067\u306f\u3001\u8868\u9762\u30da\u30d7\u30c1\u30c9\u306e\u5206\u5b50\u5f62\u614b\u304c\u5909\u5316\u3057\u3066\u5b54\u3092\u958b\u653e\u3057\u3001\u62c5\u6301\u3055\u308c\u3066\u305f\u85ac\u7269\u304c<br \/>\n\u653e\u51fa\u3055\u308c\u308b\u3002<\/p>\n<p><a href=\"https:\/\/seeds.web.nitech.ac.jp\/wp-content\/uploads\/2013\/11\/image6.png\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" src=\"https:\/\/seeds.web.nitech.ac.jp\/wp-content\/uploads\/2013\/11\/image_thumb6.png\" width=\"550\" height=\"211\" border=\"0\" \/><\/a><br \/>\n\u5468\u671f\u7684\u306b\u85ac\u7269\u5f90\u653e\u62c5\u4f53\u5468\u56f2\u306e\uff50H\u3092\u5869\u57fa\u6027\uff08\uff50H8)\u3001\u9178\u6027\uff08\uff50H6)\u3068\u5909\u5316\u3055\u305b\u305f\u969b\u306e\u3001\u85ac\u7269\u653e\u51fa\u91cf\u3002\u9178\u6027\u3067\u3001\u5927\u304d\u306a\u85ac\u7269\u306e\u653e\u51fa\u304c\u8a8d\u3081\u3089\u308c\u3001\u53ef\u9006\u7684\u306b\u85ac\u7269\u306e\u653e\u51fa\u3068\u305d\u306e\u6291\u5236\u304c\u8d77\u3053\u308b\u3053\u3068\u304c\u5206\u304b\u308b\u3002<\/p>\n<p><span style=\"font-size: medium;\"><strong><br \/>\n\u4f01\u696d\u7b49\u3078\u306e\u63d0\u6848 <\/strong><\/span><\/p>\n<p><strong>\u7814\u7a76\u8005\u304b\u3089\u306e\u30e1\u30c3\u30bb\u30fc\u30b8<\/strong><br \/>\n\u3000\u6a0b\u53e3\u7814\u7a76\u5ba4\u3067\u306f\u3001\u5206\u5b50\u306e\u81ea\u5df1\u7d44\u7e54\u5316\u3092\u7528\u3044\u3066\u5f62\u6210\u3057\u305f\u30ca\u30ce\u69cb\u9020\u4f53\u3092\u7528\u3044\u3066\u3001\u5404\u7a2e\u6a5f\u80fd\u6027\u6750\u6599\u306e\u69cb\u7bc9\u3092\u76ee\u7684\u306b\u7814\u7a76\u3057\u3066\u3044\u307e\u3059\u3002<\/p>\n<p><strong>\u6587\u732e\u30fb\u7279\u8a31<\/strong><br \/>\n\u30fb\u201cDesign of the nanocarrier having the regulated drug release ability utilizing a reversible conformational transition of peptide responded to slight pH changes\u201d, K. Murai, M. Higuchi, T. Kinoshita, and K. Kato, Phys. Chem. Chem. Phys, 15(27), 11454-11460 (2013).<\/p>\n<table class=\"seeds-head7\">\n<tbody>\n<tr>\n<td><strong>\u8a66\u4f5c\u54c1\u72b6\u6cc1<\/strong><\/td>\n<td style=\"width: 50px; background-color: #adff2f;\">\u7121\u3057<\/td>\n<td style=\"width: 50px;\">\u63b2\u793a\u53ef<\/td>\n<td style=\"width: 50px;\">\u63d0\u4f9b\u53ef<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<table class=\"seeds-head4\">\n<tbody>\n<tr>\n<td><strong>\u5229\u7528\u53ef\u80fd\u306a\u8a2d\u5099\u30fb\u88c5\u7f6e<\/strong><\/td>\n<td><strong>\u5171\u540c\u7814\u7a76\u3092\u5e0c\u671b\u3059\u308b\u30c6\u30fc\u30de<\/strong><br \/>\n\u5b9f\u7528\u5316\u7814\u7a76<br \/>\n\u7528\u9014\u958b\u767a\u7814\u7a76<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table class=\"seeds-head5\">\n<tbody>\n<tr>\n<td><strong>\u7814\u7a76\u8005\u30c7\u30fc\u30bf\u30d9\u30fc\u30b9\u3068\u306e\u30ea\u30f3\u30af<\/strong>\uff08\u540d\u524d\u3092\u30af\u30ea\u30c3\u30af\u3057\u3066\u304f\u3060\u3055\u3044\uff09<br \/>\n\u7814\u7a76\u8005\u540d\uff1a<a href=\"http:\/\/researcher.nitech.ac.jp\/html\/100000050_ja.html?l=ja&amp;k=%E6%A8%8B%E5%8F%A3&amp;o=title-a&amp;p=1\" target=\"_blank\" rel=\"noopener noreferrer\">\u6a0b\u53e3\u771f\u5f18<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<table class=\"seeds-head6\">\n<tbody>\n<tr>\n<td><a href=\"https:\/\/seeds.web.nitech.ac.jp\/wp-content\/uploads\/2013\/11\/014higuchi1.pdf\" target=\"_blank\" rel=\"noopener noreferrer\">\uff30\uff24\uff26\u8868\u793a\u3068\u5370\u5237<\/a><\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"<p>\uff5e\u50c5\u304b\u306a\u74b0\u5883\u5909\u5316\u3067\u958b\u9589\u3059\u308b\u5206\u5b50\u30b2\u30fc\u30c8\uff5e \u526f\u4f5c\u7528\u306e\u5c11\u306a\u3044\u85ac\u7269\u5f90\u653e\u62c5\u4f53\u306e\u69cb\u7bc9 \u7814\u7a76\u5206\u91ce\u5206\u985e\uff1a5303 \u9ad8\u5206\u5b50\u5316\u5b66 \u7523\u696d\u5206\u985e\uff1a\u5316\u5b66\u5de5\u696d\uff0c\u4fdd\u5065\u885b\u751f \u30ad\u30fc\u30ef\u30fc\u30c9\uff1a\u81ea\u5df1\u7d44\u7e54\u5316\u9ad8\u5206\u5b50\uff0c\u5206\u5b50\u7d20\u5b50\uff0c\u30ca\u30ce\u8868\u9762\u30fb\u754c\u9762\uff0c\u30ca\u30ce\u7d50\u6676\u6750\u6599\u30fb\u30b3\u30f3\u30dd\u30b8\u30c3 [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":"","_links_to":"","_links_to_target":""},"categories":[58],"tags":[80],"class_list":["post-1328","post","type-post","status-publish","format-standard","hentry","category-b5300","tag-t000"],"aioseo_notices":[],"_links":{"self":[{"href":"https:\/\/seeds.web.nitech.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/1328","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/seeds.web.nitech.ac.jp\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/seeds.web.nitech.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/seeds.web.nitech.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/seeds.web.nitech.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=1328"}],"version-history":[{"count":13,"href":"https:\/\/seeds.web.nitech.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/1328\/revisions"}],"predecessor-version":[{"id":4931,"href":"https:\/\/seeds.web.nitech.ac.jp\/index.php?rest_route=\/wp\/v2\/posts\/1328\/revisions\/4931"}],"wp:attachment":[{"href":"https:\/\/seeds.web.nitech.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=1328"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/seeds.web.nitech.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=1328"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/seeds.web.nitech.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=1328"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}